ACTR2 is a serine/threonine kinase receptor.
| Inventor | Institute |
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| Roy Bicknell | University of Oxford |
| SKU: | 151217 |
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| Product description: | ACTR2 is a serine/threonine kinase receptor. Activin signal transduction pathways are implicated in diverse developmental and physiological processes. Activin is implicated in control of vascular endothelial growth. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Recombinant fusion protein composed of the intracellular kinase domain of the human type 2 activin receptor fused to gluthathion S-transferase |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151217 |
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| Provenance and Ownership: | The Anti-ACTR2 149 is owned by Cancer Research UK. CancerTools supplies the Anti-ACTR2 149 under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-ACTR2 149 directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Unit size: | 100 ug |
| Research Fields: | Cell biology; Cell signaling and signal transduction; Developmental biology; Tissue-specific biology |
| Application: | IHC ; IF ; IP ; WB |
| Target: | Activin receptor type 2 (ACTR2) |
| Reactivity: | Human |
| Clone: | 149/1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | ACTR2 is a serine/threonine kinase receptor. Activin signal transduction pathways are implicated in diverse developmental and physiological processes. Activin is implicated in control of vascular endothelial growth. |
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| Format: | Liquid |
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| Concentration: | 1mg/ml |
| Storage buffer: | DMEM + 5% FCS. Thaw into DMEM + 10% FCS and 10% Iscoves and reduce to DMEM + 5% FCS |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
McCarthy SA et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363 McCarthy SA et al. 1994. J. Biol. Chem. 269(6):3909-12. PMID: 8307945 Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689. |
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