Anti-12R-LOX

Alox12b plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss.

Contributors

Inventor Institute
Peter Krieg Deutsches Krebsforschungszentrum (DKFZ)- German Cancer Research Center
SKU: 153776
Product description: Alox12b plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. Ichthyosis is a family of rare genetic skin disorders characterised by dry, thickened, scaly skin associated with mutations in Alox12b.
Alternate name: Arachidonate 12-lipoxygenase, 12R-type, 12R-LOX, 12R-lipoxygenase, Epidermis-type lipoxygenase 12. UniProt ID:O75342
Conjugation: Unconjugated
Immunogen: Mouse 12R-LOX (Y14334) Peptide Y1: aa 159-179 IPSYHPPPRRCRNPNRPEWDG Or Mouse 12R-LOX (Y14334) Peptide Y2: aa 167-189 CRNPNRPEWDGYIPGFPILINIKA
Cat. #: 153776
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cell biology; Metabolism
Application: WB
Target: Arachidonate 12-lipoxygenase (ALOX12B)
Reactivity: Human ; Mouse
Host: Rabbit
Class: Polyclonal
Target background: Alox12b plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. Ichthyosis is a family of rare genetic skin disorders characterised by dry, thickened, scaly skin associated with mutations in Alox12b.
Format: Liquid
Storage buffer: Neat sera
Shipping conditions: Dry ice

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