Cat. #158394
p110beta PI3K-floxed
Cat. #: 158394
Sub-type: Mouse
Availability: 6-8 weeks
Model: Conditional KO
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Bart Vanhaesebroeck
Institute: Ludwig Institute for Cancer Research ; The University of Edinburgh
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: p110beta PI3K-floxed
- Research fields: Cancer
- Tool sub type: Mouse
- Model: Conditional KO
- Conditional: Yes
- Genetic background: Exons 21 and 22 of the PIK3CA/p110b PI3K gene are flanked by LoxP sites - backcrossed onto C57B6/J background.
- Phenotype: Homozygous and heterozygous mice are phenotypically normal.
- Production details: Exons 21 and 22 of the PIK3CA/p110b PI3K gene are flanked by LoxP sites - backcrossed onto C57B6/J background.
- Additional notes: Homozygous and heterozygous mice are phenotypically normal.
Handling
- Shipping conditions: Embryo/Spermatoza- Dry Ice
Target Details
- Target: PIK3CB
References
- Kulkarni et al. 2011. Sci Signal. 4(168):ra23. PMID: 21487106.
- Guillermet-Guibert et al. 2008. Proc Natl Acad Sci U S A. 105(24):8292-7. PMID: 18544649.
