UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line

A human bladder cancer model used to explore EGFR-targered therapies, apoptosis signally pathways, and precision oncology approaches. Save 30% on this cell line this summer. Use code SUM26CELL at checkout.

Contributors

Inventor Institute
H. Grossman ; Anita Sabichi University of Michigan
SKU: 160438
Product description: UM-UC-7 is a human transitional cell carcinoma cell line derived from a male bladder cancer patient. The UM-UC panel of urothelial carcinoma is a diverse range of 11 patient derived cell lines developed by the university of Michigan that have been well-categorised in the literature.
Alternate name: UMUC7; University of Michigan-Urothelial Carcinoma-7
Cellosaurus ID: CVCL_2752
Disease: Cancer
Cat. #: 160438
Unit size: 1×10^6 cells / vial
Cancer types: Bladder cancer
Research Fields: Cancer
Organism: Human
Tissue: Bladder
Model: Tumourigenic cell line
Growth properties: Adherent
Cancer Types In Detail: Human bladder transitional cell carcinoma
Format: Frozen
Shipping conditions: Dry ice
Growth medium: Cells were grown in EMEM (EBSS) + 2mM Glutamine + 1% Non Essential Amino Acids (NEAA) + 10% Foetal Bovine Serum (FBS).
Subculture routine: Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4×10,000 cells/cm2; using 0.05% trypsin/EDTA; 5% CO2, 37°C. Doubling time approximately 19 hours.
References:

Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639.

Grossman et al. 1984. J Urol. 132(4):834-7. PMID: 6471236.

Images

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UM-UC-7 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

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