SVG-A Msh3 1.7X Cell Line

This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated.

Contributors

Inventor Institute
Robert Lahue National University of Ireland Galway ; Brown University
Cat. #: 153691
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Research Fields: Genetics;Neurobiology
Organism: Human
Tissue: Brain
Product description: This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated.
Additional notes: CRISPR edited cells. Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here. This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can provide the…
Parental cell line: Msh3-/- SVG-A Cell Line
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Growth medium: DMEM supplemented with 10% FBS
Mycoplasma free: Yes
Biosafety level: 1
References:

Keogh et al. 2017. MutS? abundance and Msh3 ATP hydrolysis activity are important drivers of CTGCAG repeat expansions. Nucleic Acids Res. 2017 Sep 29

45(17):10068-10078.

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