#153691

SVG-A Msh3 1.7X Cell Line

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Cat. #153691

SVG-A Msh3 1.7X Cell Line

Cat. #: 153691

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Availability: 3-5 days

Organism: Human

Tissue: Brain

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Robert Lahue

Institute: National University of Ireland Galway ; Brown University

Tool Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: SVG-A Msh3 1.7X Cell Line
  • Research fields: Genetics;Neurobiology
  • Tool sub type: Continuous
  • Parental cell: Msh3-/- SVG-A Cell Line
  • Organism: Human
  • Tissue: Brain
  • Description: This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated.
  • Biosafety level: 1
  • Additional notes: CRISPR edited cells. Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here. This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can provide the...

Applications

  • Application notes: Cancer Research Technology Limited (trading research tools as CancerTools.org) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here: https://www.cancertools.org/tool-faqs#hs_cos_wrapper_widget_1649861453796 This license from ERS Genomics Ltd allows CancerTools.org to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. CancerTools.org can provide these modified CRISPR-Cas9 cell lines to comp...

Handling

  • Format: Frozen
  • Growth medium: DMEM supplemented with 10% FBS
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice
  • Storage conditions: Liquid Nitrogen
  • Mycoplasma free: Yes

Related Tools

  • Related tools: Msh3-/- SVG-A Cell Line ; SVG-A Cell Line

References

  • Keogh et al. 2017. MutS? abundance and Msh3 ATP hydrolysis activity are important drivers of CTGCAG repeat expansions. Nucleic Acids Res. 2017 Sep 29
  • 45(17):10068-10078.