Cat. #162293
mCherry HSF-1 expressing A375 cell line (A375-756)
Cat. #: 162293
Organism: Human
Tissue: Skin
Disease: Cancer
Model: Transgenic
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Petr Muller
Institute: Masaryk Memorial Cancer Institute
Primary Citation: Simoncik et al., 2024 PLoS ONE 19(11): e0312524
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: mCherry HSF-1 expressing A375 cell line (A375-756)
- Parental cell: A375
- Organism: Human
- Gender: Female
- Tissue: Skin
- Donor: 54 years old
- Disease: Cancer
- Morphology: Epithelial
- Growth properties: Adherent
- Model: Transgenic
- Model description: Expression of fluorescently mCherry tagged Heat Shock Transcription Factor 1 (HSF1)
- Crispr: No
- Conditional: No
- Description: A375 cell line derivative expressing the fluorescently mCherry tagged Heat Shock Transcription Factor 1 (HSF1) used to study the role of HSF1 and assess proteotoxic stress by live cell imaging
- Application: Cell culture, live cell imaging
- Biosafety level: BSL-2
Target Details
- Target: HSF-1
- Target background: HSF1 is the main mediator of the stress response located in the cell nucleus, and is also involved in non-stress regulation, such as metabolism and development.
Applications
- Application: Cell culture, live cell imaging
Handling
- Format: Frozen
- Atmosphere: humidified CO2 atmosphere
- Storage conditions: Liquid Nitrogen
- Cultured in antibiotics: Yes, penicillin/streptomycin
References
- Simoncik et al., 2024 PLoS ONE 19(11): e0312524
