Cat. #157959
CCSP C12 Human Ovarian Cancer subpopulation cell line
Cat. #: 157959
Unit size: 1x10^6 cells / vial
Availability: 10-12 weeks
Organism: Human
Tissue: Ovary
Disease: Cancer
Model: Tumour line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Karl Skorecki ; Ehood Katz ; Maty Tzukerman
Institute: Rambam Health Care Campus
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: CCSP C12 Human Ovarian Cancer subpopulation cell line
- Alternate name: CCSP
- Cancer: Gynaecologic cancer
- Cancers detailed: Ovarian
- Research fields: Cancer
- Organism: Human
- Tissue: Ovary
- Disease: Cancer
- Model: Tumour line
- Description: The CCSP family of six cell lines aims to recapitulate the ovarian cancer microenvironment, and is suitable for investigation into cancer biology and cancer therapeutics research. These lines are derived from malignant ascites; a common destination for malignant ovarian cancer cells. They have been validated in direct human-to-mouse xenografts (SCID/beige mouse muscle) and human embryonic stem cell models. The CCSP lines demonstrate morphological hallmarks of ovarian cancer and are positive for clinically relevant ovarian cancer biomarkers CA-125, CA-19.9, and MUC1, as well as the epithelial-specific antigen Ber-EP4. Tumourigenicity has been confirmed for all CCSP sub-populations in the human embryonic stem cell model, and specific sub-populations in the mouse xenograft model.
Handling
- Format: Frozen
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: CCSP C16 Human Ovarian Cancer subpopulation cell line ; CCSP C13 Human Ovarian Cancer subpopulation cell line ; CCSP C1 Human Ovarian Cancer subpopulation cell line ; CCSP C2 Human Ovarian Cancer subpopulation cell line ; CCSP C5 Human Ovarian Cancer subpopulation cell line
References
- Katz et al. 2009. Clin Cancer Res. 15(1):70-80. PMID: 19118034.
