C125PM Colorectal Cell Line

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C125PM is a human colorectal adenocarcinoma cell line. Colorectal cancer (CRC) cell lines are widely used pre-clinical model systems.

Contributors

Inventor Institute
Walter Bodmer Cancer Research UK, London Research Institute: Lincoln's Inn Fields
SKU: 151763
Product description: C125PM is a human colorectal adenocarcinoma cell line.
Conditional: Yes
Cellosaurus ID: CVCL_8175
Disease: Cancer
Cat. #: 151763
Provenance and Ownership: The C125PM Colorectal Cell Line is owned by Cancer Research UK. CancerTools supplies the C125PM Colorectal Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing C125PM Colorectal Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Unit size: 1×10^6 cells / vial
Cancer types: Colorectal cancer
Research Fields: Cancer; Drug development
Organism: Human
Tissue: Colon
Model: Tumour line
Cancer Types In Detail: Adenocarcinoma
Format: Frozen
Shipping conditions: Dry ice
Growth medium: Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4×10,000 cells/cm?‹Â› using 0.05% trypsin or trypsin/EDTA; 5% CO2; 37?‚°C.
References:

Rowan et al. 2000. Proc Natl Acad Sci U S A. 97(7):3352-7. PMID: 10737795.

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".

Images

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C125PM cell line growth profile. Medium changed at 70 hours. Image courtesy of European Collection of Authenticated Cell Cultures (ECACC).
C125PM Colorectal Cell Line. 7 d post plating. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

Citations And Reviews

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