BICR 56 Cell Line

Adherent keratinocyte cell line derived from a squamous cell carcinoma of the tongue of a Caucasian female. Keratin and involucrin – BICR56 cell line

Contributors

Inventor Institute
Eric Kenneth Parkinson Cancer Research UK, Glasgow: The Beatson Institute
Cat. #: 152847
Unit size: 1×10^6 cells / vial
Cancer types: Head and neck cancer
Research Fields: Apoptosis and autophagy;Cancer;Drug development;Genetics
Organism: Human
Tissue: Tongue
Model: Tumourigenic cell line
Growth properties: Adherent
Cancer Types In Detail: Tongue squamous carcinoma
Alternate name: bicr56; BICR-56; BICR56; Beatson Institute for Cancer Research 56
Product description: Adherent keratinocyte cell line derived from a squamous cell carcinoma of the tongue of a Caucasian female. Keratin and involucrin markers present. Known mutations: p53 and p16. Cells are tumourigenic in athymic mice. Epidermal Growth Factor Receptor (EGFR) present.
Conditional: Yes
Additional notes: STR-PCR Data: Amelogenin: X CSF1PO: 12 D13S317: 12 D16S539: 11 D5S818: 11,12 D7S820: 8,12 THO1: 9,9.3 TPOX: 8,9 vWA: 15,16
Cellosaurus ID: CVCL_2313
disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
References:

Celentano et al. 2019. J Cell Physiol. 234(3):2013-2020. PMID: 30240006.

Edington et al. 1995. Mol Carcinog. 13(4):254-265. PMID: 7646764.

Images

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Characteristics of the BICR human head and neck squamous cell carcinoma (HNSCC) cell line panel, including tissue of origin, tumour (T), node (N), and metastasis (M) stage, and TP53 mutation status.

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