Cat. #152843
BICR 18 Cell Line
Cat. #: 152843
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Larynx
Disease: Cancer
Model: Tumourigenic cell line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Eric Kenneth Parkinson
Institute: Cancer Research UK, Glasgow: The Beatson Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: BICR 18 Cell Line
- Alternate name: bicr18; BICR-18; BICR18; Beatson Institute for Cancer Research 18; HNSCC; SCC-HN
- Cancer: Head and neck cancer
- Cancers detailed: Larynx squamous cell carcinoma (lymph node metastasis)
- Research fields: Apoptosis and autophagy;Cancer;Drug development;Genetics
- Organism: Human
- Gender: Male
- Tissue: Larynx
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumourigenic cell line
- Conditional: Yes
- Description: Adherent keratinocyte cell line derived from a lymph node metastasis squamous cell carcinoma (SSC) of the larynx. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. By short tandem repeat (STR)-PCR analysis the Y chromosome could not be detected in this cell line. It is a known phenomenon that SSC cell lines can lose their Y chromosome.
- Additional notes: STR-PCR Data: Amelogenin: X CSF1PO: 11,12 D13S317: 8,13 D16S539: 12,14 D5S818: 12 D7S820: 9 THO1: 7 TPOX: 9,12 vWA: 17,20
- Cellosaurus id: CVCL_2309
Applications
- Application notes: STR-PCR Data: Amelogenin: X CSF1PO: 11,12 D13S317: 8,13 D16S539: 12,14 D5S818: 12 D7S820: 9 THO1: 7 TPOX: 9,12 vWA: 17,20
Handling
- Format: Frozen
- Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: BICR 10 Cell Line ; BICR 16 Cell Line ; BICR 3 Cell Line ; BICR 56 Cell Line ; BICR 6 Cell Line ; BICR 78 Cell Line ; BICR 22 Cell Line ; BICR 31 Cell Line ; BICR 82 Cell Line
References
- Loughran et al. 1997. Oncogene. 14(16):1955-1964. PMID: 9150362.
- Edington et al. 1995. Mol Carcinog. 13(4):254-265. PMID: 7646764.
