BICR 10 Cell Line

Adherent keratinocyte cell line derived from a recurrent squamous cell carcinoma of the buccal mucosa of a Caucasian female.

Contributors

Inventor Institute
Eric Kenneth Parkinson Cancer Research UK, Glasgow: The Beatson Institute
Cat. #: 152841
Unit size: 1×10^6 cells / vial
Cancer types: Head and neck cancer
Research Fields: Apoptosis and autophagy;Cancer;Drug development;Genetics
Organism: Human
Tissue: Buccal mucosa
Model: Tumourigenic cell line
Growth properties: Adherent
Cancer Types In Detail: Buccal mucosa squamous carcinoma
Alternate name: bicr10; BICR-10; BICR10; Beatson Institute for Cancer Research 10; HNSCC; SCC-HN
Product description: Adherent keratinocyte cell line derived from a recurrent squamous cell carcinoma of the buccal mucosa of a Caucasian female. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice.
Cellosaurus ID: CVCL_2307
disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
References:

Edington et al. 1995. Mol Carcinog. 13(4):254-265. PMID: 7646764.

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