#161888

B16 PBRM1 KO1

Cat. #161888

B16 PBRM1 KO1

Cat. #: 161888

Availability: 8-10 weeks

Organism: Mouse

Tissue: Skin

Model: Genetically modified

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jessica Downs, Hugang Feng

Institute: The Institute of Cancer Research

Tool Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: B16 PBRM1 KO1
  • Cancer: Skin cancer
  • Research fields: Cancer
  • Parental cell: B16-F10
  • Clone: 1 (also called clone B4)
  • Organism: Mouse
  • Tissue: Skin
  • Morphology: mixture of spindle-shaped and epithelial-like cells
  • Growth properties: Adherent
  • Model: Genetically modified
  • Model description: PBRM1 knockout
  • Crispr: Yes
  • Conditional: No
  • Products or characteristics of interest: Gene loss-of-function, chromatin-remodelling, DNA damage, cell cycle response, regulation of t-cell-mediated cell killing.
  • Description: B16-F10 knockout for PBRM1 (clone 1, also called clone B4)
  • Application: Chromatin remodelling biology studies
  • Biosafety level: 1
  • Cellosaurus id: CVCL_0159

Applications

  • Application: Chromatin remodelling biology studies

Handling

  • Format: Frozen
  • Growth medium: DMEM + 10S + 1% Penicillin/Streptomycin
  • Temperature: 37C
  • Atmosphere: 5% CO2 in air
  • Shipping conditions: Dry ice
  • Storage conditions: Liquid Nitrogen
  • Cultured in antibiotics: 1% Penicillin/Streptomycin
  • Str profiling: See Cellosaurus profile of parental cell line

References

  • Unpublished