The expression of Y haptens is frequently elevated in colo-rectal tumours in comparison to adjacent, apparently normal tissue.
| Inventor | Institute |
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| David Baldwin | University of Nottingham |
| SKU: | 153167 |
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| Product description: | Y haptens are carbohydrate surface antigens formed by the difucosylation of Type-2-blood-group chains. The expression of Y haptens is frequently elevated in colo-rectal tumours in comparison to adjacent, apparently normal tissue. |
| Alternate name: | C14 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Myeloma used: | NS0 |
| Cat. #: | 153167 |
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| Provenance and Ownership: | The Anti-Y hapten (C14) [NCRC56] is owned by Cancer Research UK. CancerTools supplies the Anti-Y hapten (C14) [NCRC56] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Y hapten (C14) [NCRC56] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Immunology |
| Application: | FACS ; RIA |
| Target: | Y hapten |
| Reactivity: | Human |
| Clone: | NCRC56 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Y haptens are carbohydrate surface antigens formed by the difucosylation of Type-2-blood-group chains. The expression of Y haptens is frequently elevated in colo-rectal tumours in comparison to adjacent, apparently normal tissue. |
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| Format: | Liquid |
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| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Price et al. 1986. Cancer Lett. 33(1):83-9. PMID: 3768863. Association of the Y hapten with glycoproteins, glycolipids and carcinoembryonic antigen in colorectal carcinoma. Brown et al. 1983. Biosci Rep. 3(2):163-70. PMID: 6189529. A monoclonal antibody against human colonic adenoma recognizes difucosylated Type-2-blood-group chains. |
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