J144 may be used in the staining of intracellular proteins to determine tissue of origin.
| Inventor | Institute |
|---|---|
| John Kemshead | Institute of Child Health |
| Cat. #: | 151112 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction;Developmental biology;Neurobiology |
| Application: | IHC ; IF ; IP ; WB |
| Target: | Vimentin |
| Reactivity: | Human |
| Clone: | J144 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Intercellular Adhesion Molecule 3; ICAM-3; ICAM-R; CDW5; CD5 |
|---|---|
| Product description: | J144 may be used in the staining of intracellular proteins to determine tissue of origin. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Molecular weight: | 130 |
| Immunogen: | Human rhabdosarcoma cell line JR1 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Vimentin is an intermediate filament protein, which is expressed in most cells of mesodermal origin but not epithelial cells. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Doldo et al. 2015. Genes Cancer. 6(11-12):490-502. PMID: 26807202. High expression of cellular retinol binding protein-1 in lung adenocarcinoma is associated with poor prognosis. Dubicke et al. 2008. Mol Hum Reprod. 14(11):641-7. PMID: 18922847. Different secretion patterns of matrix metalloproteinases and IL-8 and effect of corticotropin-releasing hormone in preterm and term cervical fibroblasts. Oppedal et al. 1987. Histopathology. 11(4):363-74. PMID: 3596475. Immunohistochemical differentiation of neuroblastomas from other small round cell neoplasms of childhood using a panel of mono- and polyclonal antibodies. |
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