A monoclonal antibody (mAb) against human UCP3. UCPs are members of the mitochondrial anion carrier proteins (MACP) family. UCPs create proton leaks across the inner to outer mitochondrial membrane by uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. It is thought to play a role in non-shivering thermogenesis, obesity and diabetes. UCP3 is an important mediator of thermogenesis.
| Inventor | Institute |
|---|---|
| Abdo Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 158041 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | ELISA ; IHC ; WB |
| Target: | Uncoupling Protein 3 |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | A monoclonal antibody (mAb) against human UCP3. UCPs are members of the mitochondrial anion carrier proteins (MACP) family. UCPs create proton leaks across the inner to outer mitochondrial membrane by uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. It is thought to play a role in non-shivering thermogenesis, obesity and diabetes. UCP3 is an important mediator of thermogenesis. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide: KVQMLRESPF. Peptide immunogen is 100% identical in many mammals including, whales, horses, bears, apes, monkeys, elephants |
| Target background: | A monoclonal antibody (mAb) against human UCP3. UCPs are members of the mitochondrial anion carrier proteins (MACP) family. UCPs create proton leaks across the inner to outer mitochondrial membrane by uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. It is thought to play a role in non-shivering thermogenesis, obesity and diabetes. UCP3 is an important mediator of thermogenesis. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
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