Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation.
| Inventor | Institute |
|---|---|
| Kaisa Ivaska-Papaioannou ; Urpo Lamminmäki | University of Turku |
| Cat. #: | 157724 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Disease (not cancer);Metabolism |
| Application: | IF ; Fn |
| Target: | osteocalcin – partially carboxylated with Glu at position 17 and 21 |
| Reactivity: | Human |
| Host: | Human |
| Class: | Recombinant |
| Alternate name: | Uncarboxylated osteocalcin, uc-Osteocalcin, uc-OC, bone gamma-carboxyglutamic acid-containing protein, BGLAP |
|---|---|
| Product description: | Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin. Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation. Uncarboxylated osteocalcin (ucOC) may participate in the regulation of glucose metabolism, thus measurement of ucOC could be useful in evaluating interactions between bone and glucose … |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Human full-length ucOC peptide (149, Glu at positions 17, 21 and 24; C23C29 bridge) |
| Target background: | Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin. Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation. Uncarboxylated osteocalcin (ucOC) may participate in the regulation of glucose metabolism, thus measurement of ucOC could be useful in evaluating interactions between bone and glucose … |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
| References: |
Arponen et al. 2020. Calcif Tissue Int. 107(6):529-542. PMID: 32839842. |
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