Monoclonal antibody directed against Thy-1 thymocyte antigen.
| Inventor | Institute |
|---|---|
| Mike Waterfield | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151074 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Cancer;Immunology;Neurobiology;Stem cell biology |
| Application: | FACS ; IHC ; IP |
| Target: | Thy1 (CDw90) |
| Reactivity: | Human |
| Clone: | aThy-1A1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Monoclonal antibody directed against Thy-1 thymocyte antigen. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Molecular weight: | 310 kDa |
| Immunogen: | Purified Thy-1. |
| Immunogen Uniprot ID: | P04216 |
| Target background: | Thy-1 is a GPI-anchored glycoprotein expressed in the brain, thymocytes and T lymphocytes. Anti-thy-1A1 has use in bone marrow purging. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Stocco et al. 2019. Front Cell Dev Biol. 7:323. PMID: 31921840. Prado et al. 2015. BMC Vet Res. 11:281. PMID: 26555093. Favaron et al. 2014. PLoS One. 9(2):e95575. PMID: 24918429. Cotmore et al. 1981. Eur J Immunol. 11(8):597-603. PMID: 7274325. Purification of Thy-1-related glycoproteins from human brain and fibroblasts: comparisons between these molecules and murine glycoproteins carrying Thy-1.1 and Thy-1.2 antigens. |
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