Anti-TCPb [F39P7F11]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-TCPb [F39P7F11]
• Research fields: Apoptosis and autophagy;Cancer;Cell biology
• Clone: F39 P7 F11
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Strain: Balb/c
• Reactivity: Human ; Mouse ; Rat ; Xenopus laevis ; Salmon
• Host: Mouse
• Application: ELISA ; IHC ; WB
• Description: The chaperonins are key molecular complexes, which are essential in the folding of proteins to produce stable and functionally competent protein conformations. One member of the chaperonin group of proteins is TCP1 (chaperonin containing t-complex polypeptide 1, or CCT), but little is known about this protein in tumours.
• Immunogen: C-terminal peptide with sequence RKRVPDHHPC conjugated to ovalbumin
• Isotype: IgG2a kappa
• Myeloma used: P3X63Ag8.653

Target Details

• Target: T-complex protein 1, beta subunit
• Target background: The chaperonins are key molecular complexes, which are essential in the folding of proteins to produce stable and Fnly competent protein conformations. One member of the chaperonin group of proteins is TCP1 (chaperonin containing t-complex polypeptide 1, or CCT), but little is known about this protein in tumours.

Applications

• Application: ELISA ; IHC ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Coghlin et al. 2006. J Pathol. 210(3):351-7. PMID: 16981251.
• Characterization and over-expression of chaperonin t-complex proteins in colorectal cancer.