TAO1 is a microtubule affinity-regulating kinase kinase (also known as MARKK) and an important regulator of mitotic progression, required for proper attachment of chromosomes to microtubules. The kinase is also important for the orientation of the mitotic spindle. TAO1 is thought to be the upstream activating kinase of MARK1, a Par family protein
| Inventor | Institute |
|---|---|
| Viji Draviam Sastry | University of Cambridge |
| Cat. #: | 152748 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology |
| Application: | IF ; WB |
| Target: | TAO1 |
| Reactivity: | Human |
| Clone: | TAO12.1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | TAO1 is a microtubule affinity-regulating kinase kinase (also known as MARKK) and an important regulator of mitotic progression, required for proper attachment of chromosomes to microtubules. The kinase is also important for the orientation of the mitotic spindle. TAO1 is thought to be the upstream activating kinase of MARK1, a Par family protein |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Molecular weight: | 120 kDa |
| Immunogen: | His-tagged recombinant human TAO1 (722-1001) generated in E.coli |
| Target background: | TAO1 is a microtubule affinity-regulating kinase kinase (also known as MARKK) and an important regulator of mitotic progression, required for proper attachment of chromosomes to microtubules. The kinase is also important for the orientation of the mitotic spindle. TAO1 is thought to be the upstream activating kinase of MARK1, a Par family protein |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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