![Western blot performed using Anti-TAO1 [TAO1 1.2]. HeLa cells were transfected with Negative control siRNA (Neg) or TAO1 siRNAs to assess the extent of protein depletion.](https://cancertools.org/wp-content/uploads/8f2e01da-94f9-4b88-9f77-1647acdc8d3d.jpg)
Cat. #151777
Anti-TAO1 [TAO1 1.2]
Cat. #: 151777
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: TAO1
Class: Monoclonal
Application: IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Viji Draviam Sastry
Institute: University of Cambridge
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-TAO1 [TAO1 1.2]
- Research fields: Cancer;Cell biology
- Clone: TAO1 1.2
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 120 kDa
- Reactivity: Human
- Host: Mouse
- Application: IF ; WB
- Description: TAO1 is a microtubule affinity-regulating kinase kinase (also known as MARKK) and an important regulator of mitotic progression, required for proper attachment of chromosomes to microtubules. The kinase is also important for the orientation of the mitotic spindle. TAO1 is thought to be the upstream activating kinase of MARK1, a Par family protein
- Immunogen: His-tagged recombinant human TAO1 (722-1001) generated in E.coli
- Isotype: IgG2b
- Recommended controls: Lysate from HeLa cell line
Target Details
- Target: TAO1
- Molecular weight: 120 kDa
- Tissue cell line specificity: Lysate from HeLa cell line
- Target background: TAO1 is a microtubule affinity-regulating kinase kinase (also known as MARKK) and an important regulator of mitotic progression, required for proper attachment of chromosomes to microtubules. The kinase is also important for the orientation of the mitotic spindle. TAO1 is thought to be the upstream activating kinase of MARK1, a Par family protein
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Shrestha et al. 2014. Open Biol. 4(6):130108. PMID: 24898139.
- TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.
