Cat. #151728
Anti-SIGLEC3 [CD33 1C7/1]
Cat. #: 151728
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: CD33
Class: Monoclonal
Application: ELISA ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Paul Crocker
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-SIGLEC3 [CD33 1C7/1]
- Alternate name: Sialic Acid Binding Ig Like Lectin 12; SIGLECL1; SLG 3; Siglec-12; Siglec-L1; S2V
- Research fields: Cancer;Cell biology;Immunology;Stem cell biology
- Clone: CD33 1C7/1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; WB
- Description: CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on and a useful marker for peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
- Immunogen: Extracellular portion of CD33 fused to the Fc portion of human IgG1
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: CD33
- Target background: CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on and a useful marker for peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
Applications
- Application: ELISA ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -80° C
- Shipping conditions: Shipping at 4° C
References
- Taylor et al. 1999. J Biol Chem. 274(17):11505-12. PMID: 10206955.
- The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.
- Freeman et al. 1995. Blood. 85(8):2005-12. PMID: 7718872.
- Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.
