Cat. #152653
Anti-SGT [6A4]
Cat. #: 152653
Unit size: 100 ug
Availability: 10-12 weeks
Target: Small glutamine-rich TPR-repeat containing protein
Class: Monoclonal
Application: IF ; WB
Reactivity: Virus
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-SGT [6A4]
- Research fields: Apoptosis and autophagy;Cell biology;Cell signaling and signal transduction;Microbiology
- Clone: 6A4
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: IF ; WB
- Description: The small glutamine-rich tetratricopeptide repeat (SGT) containing protein, also known as viral protein U (Vpu)-binding protein, was identified as a host protein that interacted with the non-structural (NS) protein of parvovirus. A subsequent study showed that SGT interacts with human immunodeficiency virus-1 (HIV-1) Vpu and Gag proteins, suggesting that SGT may play a role in HIV-1 virus assembly or release. Recently, it has been shown to interact with the SARS-CoV 7a protein but the biological significance of the interaction between 7a and SGT remains to be elucidated.
- Immunogen: GST-SGT fusion protein
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Small glutamine-rich TPR-repeat containing protein
- Target background: The small glutamine-rich tetratricopeptide repeat (SGT) containing protein, also known as viral protein U (Vpu)-binding protein, was identified as a host protein that interacted with the non-structural (NS) protein of parvovirus. A subsequent study showed that SGT interacts with human immunodeficiency virus-1 (HIV-1) Vpu and Gag proteins, suggesting that SGT may play a role in HIV-1 virus assembly or release. Recently, it has been shown to interact with the SARS-CoV 7a protein but the biological significance of the interaction between 7a and SGT remains to be elucidated.
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
