Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to […]
| Institute |
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| A*STAR Accelerate Technologies Pte Ltd |
| Cat. #: | 152645 |
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| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | IF ; WB |
| Target: | SARS coronavirus nucleocapsid protein |
| Reactivity: | Virus |
| Clone: | 6H3 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Nucleoprotein, Protein N, SARS coronavirus N protein, SARS CoV |
|---|---|
| Product description: | Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions. |
| Conjugation: | Unconjugated |
| Isotype: | Inconclusive |
| Immunogen: | GST-N (residues 121-422) |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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