Cat. #152611
Anti-RUNX3 [K12P3F11*C9]
Cat. #: 152611
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Runt-related transcription factor 3
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-RUNX3 [K12P3F11*C9]
- Research fields: Genetics
- Clone: K12P3F11*C9
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 44 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Runx3 (also known as AML2 and CBF alpha 3) forms a heterodimer with a beta subunit. The complex binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- Immunogen: Peptide QFDRSFPTL
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
- Recommended controls: WB - Jurkat cell lysates; IHC- formalin-fixed, paraffin-embedded multi tumour tissue microarray
Target Details
- Target: Runt-related transcription factor 3
- Molecular weight: 44 kDa
- Tissue cell line specificity: WB - Jurkat cell lysates; IHC- formalin-fixed, paraffin-embedded multi tumour tissue microarray
- Target background: Runx3 (also known as AML2 and CBF alpha 3) forms a heterodimer with a beta subunit. The complex binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
