Cat. #153994
Anti-RAP [7F1]
Cat. #: 153994
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: 39-kDa receptor-associated protein (RAP)
Class: Monoclonal
Application: WB ; IHC ; ELISA
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Maryland
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-RAP [7F1]
- Alternate name: Receptor Associated Protein antibody
- Research fields: Cell signaling and signal transduction;Genetics;Neurobiology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 39 kDa
- Reactivity: Human
- Host: Mouse
- Application: WB ; IHC ; ELISA
- Description: LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. Expression of LRP1 requires RAP, a molecular chaperone of LRP1.
- Immunogen: human RAP
- Isotype: IgG1
Target Details
- Target: 39-kDa receptor-associated protein (RAP)
- Molecular weight: 39 kDa
- Tissue cell line specificity: Mouse
- Target background: LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Fnly, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. Expression of LRP1 requires RAP, a molecular chaperone of LRP1.
Applications
- Application: WB ; IHC ; ELISA
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Coukos et al. 1994. Am J Pathol. 144(2):383-92. PMID: 7508685.
- Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
