Cat. #151269
Anti-Rad51D [Rad51D 5B3/6]
Cat. #: 151269
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Rad51D
Class: Monoclonal
Application: IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Rad51D [Rad51D 5B3/6]
- Research fields: Genetics
- Clone: Rad51D 5B3/6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IP ; WB
- Description: RAD51D is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51D is also a component for the homologous recombination pathway.
- Immunogen: His-tagged human Rad51D, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Rad51D
- Target background: RAD51D is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51D is also a component for the homologous recombination pathway.
Applications
- Application: IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
- Identification and purification of two distinct complexes containing the five RAD51 paralogs.
- Kawabata et al. 1999. Biochem Biophys Res Commun. 257(1):156-62. PMID: 10092526.
- Multiple alternative transcripts of the human homologue of the mouse TRAD/R51H3/RAD51D gene, a member of the rec A/RAD51 gene family.
- Pittman et al. 1998. Genomics. 49(1):103-11. PMID: 9570954.
- Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene.
