Cat. #151401
Anti-Proliferation marker [JC1] mAb
Cat. #: 151401
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Proliferation marker
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Proliferation marker [JC1] mAb
- Research fields: Cancer;Cell biology;Neurobiology
- Clone: JC1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 212 kDa and 123 kDa
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: JC1 detects a nuclear antigen, distinct from Ki67, present in proliferating cells. It is useful as a marker of proliferation in cases such as squamous cell carcinoma where the Ki67 index cannot be determined.
- Immunogen: Pokeweed-stimulated lymphocytes
- Isotype: IgG2a
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Proliferation marker
- Molecular weight: 212 kDa and 123 kDa
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Li et al. 2017. J Exp Clin Cancer Res. 36(1):58. PMID: 28427443.
- Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2.
- Wang et al. 2016. Am J Cancer Res. 6(6):1331-44. PMID: 27429847.
- EMMPRIN, SP1 and microRNA-27a mediate physcion 8-O-?-glucopyranoside-induced apoptosis in osteosarcoma cells.
- Zhang et al. 2016. J Med Chem. 59(7):3562-8. PMID: 27006991.
- Unexpected Discovery of Dichloroacetate Derived Adenosine Triphosphate Competitors Targeting Pyruvate Dehydrogenase Kinase To Inhibit Cancer Proliferation.
- Garrido et al. 1992. J Clin Pathol. 45(10):860-5. PMID: 1430255.
- Monoclonal antibody JC1: new reagent for studying cell proliferation.
