#153471

Anti-PIWIL3 [Z83]

Cat. #153471

Anti-PIWIL3 [Z83]

Cat. #: 153471

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Piwi Like RNA-Mediated Gene Silencing 3

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-PIWIL3 [Z83]
  • Alternate name: Anti-PIWIL3 antibody, HIWI3 antibody, Piwi like 3 antibody, PIWL3_HUMAN antibody
  • Cancer: Gynaecologic cancer
  • Cancers detailed: Ovarian
  • Research fields: Developmental biology;Genetics;Stem cell biology
  • Clone: Z83
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: PIWIL3 may play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL3 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. PIWIL3 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a D...
  • Immunogen: Ovalbumin-conjugated synthetic peptide PNRSLSTRLFYL- peptide immunogen is identical in primates
  • Isotype: IgG
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: IHC- formalin-fixed, paraffin-embedded multi tumour tissue microarray; Western Blot - Jurkat and Hela cell lysates

Target Details

  • Target: Piwi Like RNA-Mediated Gene Silencing 3
  • Tissue cell line specificity: Mouse
  • Target background: PIWIL3 may play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL3 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. PIWIL3 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a D...

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C