Cell-cell adhesion via plasma-membrane adhesion molecules, cell recognition, diapedesis, extracellular matrix organization, glomerular endothelium development, homophilic cell adhesion via plasma membrane adhesion molecules, leukocyte cell-cell adhesion, leukocyte migration, neutrophil degranulation, neutrophil extravasation, phagocytosis, platelet degranulation, signal transduction
| Inventor | Institute |
|---|---|
| Peter Newman | Versiti Blood Research Institute |
| Cat. #: | 153744 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | ELISA ; FACS ; IP ; WB |
| Target: | PECAM 1 Cytoplasmic Domain |
| Reactivity: | Bovine ; Human ; Rabbit |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD-31 |
|---|---|
| Product description: | Cell-cell adhesion via plasma-membrane adhesion molecules, cell recognition, diapedesis, extracellular matrix organization, glomerular endothelium development, homophilic cell adhesion via plasma membrane adhesion molecules, leukocyte cell-cell adhesion, leukocyte migration, neutrophil degranulation, neutrophil extravasation, phagocytosis, platelet degranulation, signal transduction |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 130 kDa |
| Immunogen: | Intracellular cytoplasmic domain, final 15 amino acids |
| Target background: | Cell-cell adhesion via plasma-membrane adhesion molecules, cell recognition, diapedesis, extracellular matrix organization, glomerular endothelium development, homophilic cell adhesion via plasma membrane adhesion molecules, leukocyte cell-cell adhesion, leukocyte migration, neutrophil degranulation, neutrophil extravasation, phagocytosis, platelet degranulation, signal transduction |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Goldberger et al. 1994. J Biol Chem. 269(25):17183-91. PMID: 8006026. Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form. |
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