PD-ECGF expression is elevated in breast tumours and is a prognostic factor in colon tumours.
| Inventor | Institute |
|---|---|
| Roy Bicknell | University of Oxford |
| Cat. #: | 151220 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Immunology;Tissue-specific biology |
| Application: | IHC ; IF ; IP ; WB |
| Target: | Platelet-derived endothelial cell growth factor (thymidine phosphorylase); PD-ECGF. |
| Reactivity: | Human |
| Clone: | PGF 44C |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | PD-ECGF expression is elevated in breast tumours and is a prognostic factor in colon tumours. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 55 kDa (reduced) |
| Immunogen: | Full length human protein in E. coli |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | PD-ECGF expression is elevated in breast tumours and is a prognostic factor in colon tumours. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Weng et al. 2012. Basic Clin Pharmacol Toxicol. 110(3):298-306. PMID: 21973306. Enhancement of mitomycin C-induced cytotoxicity by curcumin results from down-regulation of MKK1/2-ERK1/2-mediated thymidine phosphorylase expression. Ko et al. 2011. J Pharmacol Exp Ther. 338(1):184-94. PMID: 21444628. Up-regulation of extracellular signal-regulated kinase 1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small-cell lung cancer cells. Giatromanolaki et al. 2003. J Pathol. 200(2):222-8. PMID: 12754744. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. Fox et al. 1997. Ann Oncol. 8(3):271-5. PMID: 9137797. Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF. Fox et al. 1995. J Pathol. 176(2):183-90. PMID: 7636628. Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: an immunohistochemical study. Moghaddam et al. 1995. Proc Natl Acad Sci U S A. 92(4):998-1002. PMID: 7532308. Thymidine phosphorylase is angiogenic and promotes tumor growth. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151024 | Anti-Hairy [1/24] |
Key Info
Anti-Hairy [1/24]
|
View Tool | |||||||||||||||||||
| 151029 | Anti-HSVICP8 [11E2] |
Key Info
Anti-HSVICP8 [11E2]
|
View Tool | |||||||||||||||||||
| 151017 | Anti-MBP [R29.6] |
Key Info
Anti-MBP [R29.6]
|
View Tool | |||||||||||||||||||
| 151028 | Anti-Cytochrome P450 2C2, 2B1/2 [h7] |
Key Info
Anti-Cytochrome P450 2C2, 2B1/2 [h7]
|
View Tool | |||||||||||||||||||
| 151039 | Anti-Integrin aVb3 [23C6] |
Key Info
Anti-Integrin aVb3 [23C6]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.