Neuron specific enolase (NSE, or gamma-isozyme of enolase) is found at elevated concentrations in plasma in certain neoplasias, including paediatric neuroblastoma and small cell lung cancer.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 151866 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Developmental biology;Metabolism;Neurobiology;Stem cell biology |
| Application: | ELISA ; IHC ; WB |
| Target: | Gamma-isozyme of human enolase (NSE) |
| Reactivity: | Human |
| Clone: | NSEP1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Neuron specific enolase (NSE, or gamma-isozyme of enolase) is found at elevated concentrations in plasma in certain neoplasias, including paediatric neuroblastoma and small cell lung cancer. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Ovalbumin-conjugated synthetic peptides corresponding to human NSE amino acid sequence:NSE-P1: aa's 416-433 – LGDEARFAGHNFRNPSVL |
| Target background: | Neuron specific enolase (NSE, or gamma-isozyme of enolase) is found at elevated concentrations in plasma in certain neoplasias, including paediatric neuroblastoma and small cell lung cancer. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Murray et al. 1993. J Clin Pathol. 46(11):993-6. PMID: 8254105. Immunohistochemistry of neurone specific enolase with gamma subunit specific anti-peptide monoclonal antibodies. Duncan et al. 1992. J Immunol Methods. 151(1-2):227-36. PMID: 1629611. A simple enzyme-linked immunosorbent assay (ELISA) for the neuron-specific gamma isozyme of human enolase (NSE) using monoclonal antibodies raised against synthetic peptides corresponding to isozyme sequence differences. |
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