#160705

Anti-MR1 [8G3]

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Cat. #160705

Anti-MR1 [8G3]

Cat. #: 160705

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-5 days

Target: MR1

Class: Monoclonal

Application: IP ; WB

Reactivity: Human ; Mouse

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jose Villadangos ; Hamish McWilliam

Institute: University of Melbourne

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-MR1 [8G3]
  • Alternate name: Major histocompatability complex class I-related gene protein
  • Research fields: Cancer;Immunology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 42 kDa
  • Strain: C57BL/6
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Application: IP ; WB
  • Description: MR1 presents small metabolite antigens from diverse microbes to activate an abundant T cell population called mucosal associated invariant T cells (MAIT cells). In this way MR1 activates MAIT cells which results in anti-microbial immunity and tissue repair.
  • Immunogen: Peptide sequence from MR1: pwmaenlapdhwer
  • Immunogen uniprot id: Q95460
  • Isotype: IgG2a kappa
  • Myeloma used: Sp2/0
  • Recommended controls: The peptide or a lysate of cells expressing MR1

Target Details

  • Target: MR1
  • Molecular weight: 42 kDa
  • Tissue cell line specificity: The peptide or a lysate of cells expressing MR1
  • Target background: MR1 presents small metabolite antigens from diverse microbes to activate an abundant T cell population called mucosal associated invariant T cells (MAIT cells). In this way MR1 activates MAIT cells which results in anti-microbial immunity and tissue repair.

Applications

  • Application: IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • McWilliam et al. 2020. Proc Natl Acad Sci U S A. 117(40):24974-24985. PMID: 32958637.