Cat. #154752
Anti-MHC class II HLA-DQ [SPVL3]
Cat. #: 154752
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: MHC class II HLA-DQ
Class: Monoclonal
Application: FACS ; IHC ; IP
Reactivity: Human ; Pig
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-MHC class II HLA-DQ [SPVL3]
- Research fields: Cell signaling and signal transduction;Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human ; Pig
- Host: Mouse
- Application: FACS ; IHC ; IP
- Description: HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an ÄÂ?ÄÂ? heterodimer of type MHC class II. The ÄÂ? and ÄÂ? chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3. Both ÄÂ?-chain and ÄÂ?-chain vary greatly. A person often produces two ÄÂ?-chain and two ÄÂ?-chain variants and thus 4 isoforms of DQ.
- Immunogen: Cloned cytotoxic T lymphocytes.
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: MHC class II HLA-DQ
- Target background: HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an a? heterodimer of type MHC class II. The a and ? chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3. Both a-chain and ?-chain vary greatly. A person often produces two a-chain and two ?-chain variants and thus 4 isoforms of DQ.
Applications
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- te Velde et al. 1988. J Immunol. 140(5):1548-54. PMID: 3279117.
- Spits et al. 1984. Eur J Immunol. 14(4):299-304. PMID: 6609821.
- Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.
