Anti-Ly-49A [YE1/32.8.5]

The Ly-49A receptor recognizes H-2Dd and H-2Dk.

Contributors

Inventor Institute
Fumio Takei BC Cancer
Cat. #: 160511
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Immunology
Application: IP ; FACS
Target: Ly-49A
Reactivity: Mouse
Host: Rat
Class: Monoclonal
Product description: The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk.
Conjugation: Unconjugated
Isotype: IgG2b
Molecular weight: 44 kDa
Immunogen: ECA17.9.8 cells
Myeloma used: Y3
Target background: The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk.
Format: Liquid
Shipping conditions: Dry ice
References:

Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883.

Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191.

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