Cat. #151344
Anti-Leu1 [Y2/178]
Cat. #: 151344
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Leu1 (CD5)
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Leu1 [Y2/178]
- Alternate name: CD5 Molecule 2; Lymphocyte Antigen T1/Leu-1; LEU1; CD5 Antigen; T1
- Cancer: Blood cancer
- Cancers detailed: Leukemia;Lymphoma
- Research fields: Immunology;Stem cell biology
- Clone: Y2/178
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP ; WB
- Description: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis.
- Immunogen: Normal lymphocytes treated with PHA (phytohaemagglutinin)
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Leu1 (CD5)
- Tissue cell line specificity: Mouse
- Target background: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis.
Applications
- Application: FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Hassan et al. 2006. Mol Cell Biol. 26(17):6727-38. PMID: 16914752.
- CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.
