This antibody can be used for research into lactase processing.
| Inventor | Institute |
|---|---|
| Dallas Swallow | University College London (UCL) |
| Cat. #: | 151688 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell signaling and signal transduction;Metabolism |
| Application: | WB |
| Target: | Human lactase |
| Reactivity: | Human |
| Clone: | 6G11 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | AKA: Mlac1 – [6G11] |
|---|---|
| Product description: | This antibody can be used for research into lactase processing. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Affinity purified human lactase |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | This antibody can be used for research into lactase processing. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Harvey et al. 1995. Gut. 36(1):28-33. PMID: 7890232. Studies on the expression of intestinal lactase in different individuals. Maiuri et al. 1991. Gastroenterology. 100(2):359-69. PMID: 1702075. Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia. |
|---|
SDS-PAGE gel electrophoresis and immunoblotting of 13 representative samples with normal histology. Individuals number 20; 9; 3; 58; 29 and 48 are lactase non-persistent (N) and the others are lactase persistent (P). The position so the molecular weight makers 200K; 97.4K and 69K are shown to the left of the gel. The arrows on the right show the positions of the precursor polypeptides (Pre) and the mature polypeptides (Mat). Image from Harvey et al – see references

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