Monoclonal antibody directed keratin 14, with use in identifying squamous cell carcinoma, and distinguishing basal breast carcinomas.
| Inventor | Institute |
|---|---|
| Birgit Lane | Queen Mary University of London |
| Cat. #: | 151441 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | FACS ; IHC ; IF ; WB |
| Target: | Keratin 14 |
| Reactivity: | Human ; Mouse ; Pig |
| Clone: | LL002 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Monoclonal antibody directed keratin 14, with use in identifying squamous cell carcinoma, and distinguishing basal breast carcinomas. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG3 |
| Molecular weight: | 50 kDa |
| Immunogen: | The last 16 carboxy-terminal amino acids of human keratin, in the form of a synthetic peptide. This was coupled to thyroglobulin by the extra Cys added at the N terminus. |
| Immunogen Uniprot ID: | P02533 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Monoclonal antibody directed keratin 14, with use in identifying squamous cell carcinoma, and distinguishing basal breast carcinomas. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Hagiyama et al. 2017. Front Physiol. 8:997. PMID: 29259558. Kuga et al. 2016. Sci Rep. 6:26557. PMID: 27222304. Haikala et al. 2016. Cell Cycle. 15(3):316-23. PMID: 26873145. Bohn et al. 2010. Int J Clin Exp Pathol. 3(6):600-7. PMID: 20661408. p16INK4a expression in basal-like breast carcinoma. Kurzrock et al. 2008. Am J Physiol Renal Physiol. 294(6):F1415-21. PMID: 18367656. Label-retaining cells of the bladder: candidate urothelial stem cells. Purkis et al. 1990. J Cell Sci. 97 ( Pt 1):39-50. PMID: 1701769. Antibody markers of basal cells in complex epithelia. Schaafsma et al. 1990. Am J Pathol. 136(2):329-43. PMID: 1689541. Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on changing expression patterns during tumor progression. |
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