Cat. #153430
Anti-Keratin 10 [LHP1]
Cat. #: 153430
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Keratin 10
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Irene Leigh
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Keratin 10 [LHP1]
- Alternate name: CK 1 antibody, CK-1 antibody, Cytokeratin-1 antibody, EHK antibody, K1 antibody, K1C1_HUMAN antibody, Keratin 1 antibody, Keratin 1 type I antibody, Keratin antibody, Keratin type i cytoskeletal 1 antibody, Keratin type I cytoskeletal 59 kDa antibody,Keratin-1 antibody, Keratin1 antibody, KPP antibody, KRT1 antibody, type I cytoskeletal 1 antibody
- Research fields: Cancer;Cell biology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 1 and 10 are differentiation-specific keratins that are the predominant keratins in suprabasal keratinocytes in stratified epthelia. Keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. Mutations in keratins 1 and 10 cause epidermolytic hyperkeratosis.
- Immunogen: Epidermis from Psoriasis patient (crude extract)
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Keratin 10
- Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 1 and 10 are differentiation-specific keratins that are the predominant keratins in suprabasal keratinocytes in stratified epthelia. Keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. Mutations in keratins 1 and 10 cause epidermolytic hyperkeratosis.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Lane et al. 1985. Ann N Y Acad Sci. 455:241-58. PMID: 2417515.
- Keratin antigens in differentiating skin.
