Glycoprotein IIb/IIIa, also known as integrin aIIb?Ÿ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann’s thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
| Inventor | Institute |
|---|---|
| Richard Aster | Versiti Blood Research Institute |
| Cat. #: | 153748 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | FACS |
| Target: | Integrin Beta 3a (GPIIIa, CD61)ÄÂĂÂ |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD-61 |
|---|---|
| Product description: | Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Molecular weight: | ~ 86-87 kDa |
| Immunogen: | EGF repeats |
| Target background: | Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151019 | Anti-Mos [S3.1] |
Key Info
Anti-Mos [S3.1]
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| 151023 | Anti-IL12 [1-1D5] |
Key Info
Anti-IL12 [1-1D5]
|
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| 151035 | Anti-CD8 [14] mAb |
Key Info
Anti-CD8 [14] mAb
|
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| 151039 | Anti-Integrin aVb3 [23C6] |
Key Info
Anti-Integrin aVb3 [23C6]
|
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| 151040 | Anti-CD11 & CD18 [24] |
Key Info
Anti-CD11 & CD18 [24]
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