Cat. #153745
Anti-Integrin Beta 3 (GPIIIa, CD61) [AP-2]
Cat. #: 153745
Unit size: 100 ug
Target: Integrin Beta 3 (GPIIIa, CD61)ÄÂĂÂ
Class: Monoclonal
Application: ELISA ; FACS
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Richard Aster
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Integrin Beta 3 (GPIIIa, CD61) [AP-2]
- Alternate name: CD-61
- Research fields: Immunology
- Class: Monoclonal
- Conjugation: Unconjugated
- Host: Mouse
- Application: ELISA ; FACS
- Description: Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
- Immunogen: Human platelet
- Isotype: IgG1
Target Details
- Target: Integrin Beta 3 (GPIIIa, CD61)ÄÂĂÂ
- Target background: Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Applications
- Application: ELISA ; FACS
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Pidard et al. 1983. J Biol Chem. 258(20):12582-6. PMID: 6226659.
- Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.
