Anti-Inhibin a [PO12/8]

Clone PO 12/8 is useful in detecting inhibin a levels, especially in prostate cancer cells.

Contributors

Institute
BioServ UK Ltd
Cat. #: 153647
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell signaling and signal transduction
Application: ELISA ; IHC
Target: Inhibin a
Reactivity: Human
Clone: PO12/8
Host: Mouse
Class: Monoclonal
Alternate name: Inhibin alpha chain, INHA
Product description: Higher levels of inhibin Î? have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin Î? levels, especially in prostate cancer cells.
Conjugation: Unconjugated
Isotype: IgG2a
Molecular weight: 40 kDa
Immunogen: Synthetic peptide corresponding to epitope region aa73-96 of the aC region of a subunit of inhibin A
Myeloma used: Sp2/0-Ag14
Target background: Higher levels of inhibin a have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin a levels, especially in prostate cancer cells.
Format: Liquid
Shipping conditions: Dry ice
References:

Balanathan et al. 2009. Br J Cancer. 100(11):1784-93. PMID: 19436293.

Elevated level of inhibin-alpha subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer.

Risbridger et al. 2004. Mol Cell Endocrinol. 225(1-2):73-6. PMID: 15451570.

Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer.

Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.

Development of an inhibin alpha subunit ELISA with broad specificity.

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