Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes.
| Institute |
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| University of Cambridge |
| Cat. #: | 154012 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction;Metabolism |
| Target: | Human Insulin receptor |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | IR, hIR, INSR |
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| Product description: | Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Molecular weight: | 135 kDa |
| Immunogen: | Affinity-purified human insulin receptor |
| Myeloma used: | NS0 |
| Target background: | Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Soos et al. 1986. Biochem J. 235(1):199-208. PMID: 2427071. Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor. |
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