A site specific polyclonal antibody for HSPB3 also known as HSP27L. HSP27L target means this reagent can be used to confirm the presence of HSPB1 in cancer as well as HSPB3
| Inventor | Institute |
|---|---|
| Roy Quinlan | University of Durham |
| Cat. #: | 162214 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | WB ; IHC |
| Target: | HSPB3 |
| Reactivity: | Human |
| Class: | Polyclonal |
| Alternate name: | HSP27, HSPL27, Heat shock 17 kDa protein (HSP 17), protein 3 |
|---|---|
| Product description: | A polyclonal antibody for HSPB3 also known as HSP27 or HSP27L. This antibody binds a site on the C-terminus of the protein. As it is a HSP27L antibody, this reagent can be used to confirm the presence of HSPB1 as well as HSPB3. |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Molecular weight: | 20kDa, 150 residues |
| Immunogen: | peptide crosslinked to KLH |
| Target background: | A small heat-shock protein. Small heat-shock proteins are characterized by a conserved sequence of 80 to 100 amino acids, often called the alpha-crystallin domain, and range in size from 12 to 43 kD in the monomeric state; as multimeric complexes, they range from 150 to 800 kD . |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1mg/ml |
| Storage buffer: | Serum plus azide (0.02%) |
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Gianniou DD, et al. 2023. Int J Mol Sci. 30 24(3):2609. PMID: 36768927. |
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