FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases.
| Institute |
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| University of Illinois Chicago |
| Cat. #: | 156384 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Drug development;Genetics |
| Application: | WB ; IP ; ChIP ; ELISA ; IHC |
| Target: | Forkhead Box M1 |
| Reactivity: | Human |
| Host: | Rabbit |
| Class: | Polyclonal |
| Alternate name: | FoxM1 |
|---|---|
| Product description: | FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma. |
| Conjugation: | Unconjugated |
| Immunogen: | His-tagged FoxM1b, 365-748 amino acids |
| Target background: | FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Wang et al. 2005. Mol Cell Biol. 25(24):10875-94. PMID: 16314512. |
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