Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, […]
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151359 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology;Stem cell biology |
| Application: | FACS ; IHC; IP |
| Target: | Fc gamma Recptor II (FCGR2, CD32) |
| Reactivity: | Human |
| Clone: | KB61 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Fc Fragment Of IgG Receptor IIb; IgG Fc Receptor II-B; Fc-Gamma-RIIb; FcRII-B; CDw32; IGFR2; FCG2; CD32; FCGR2; CD32B |
|---|---|
| Product description: | Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Hairy cell leukaemia cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Greenman J et al. 1991. Mol Immunol 28:1243-54. PMID: 1835758 Pulford K et al. 1986. Immunology 57:71-6. PMID: 3484721 Matsumoto K et al, J Immunol. 2004 Feb 15 172(4):2186-93. PMID: 14764685 |
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