Cat. #151822
Anti-FANCM [CV5.1] mAb
Cat. #: 151822
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Human FANCM (Fanconi anemia, complementation group M)
Class: Monoclonal
Application: IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-FANCM [CV5.1] mAb
- Alternate name: Fanconi Anemia Complementation Group M; KIAA1596; Fanconi Anemia-Associated Polypeptide Of 25 Kda; ATP-Dependent RNA Helicase FANCM; Protein Hef Ortholog; FAAP25
- Research fields: Genetics
- Clone: CV5.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IF ; IP ; WB
- Description: Fanconi anemia, complementation group M. Fanconi anemia-associated polypeptide of 250 kDa. ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
- Immunogen: His-tagged denatured FANCM (aa 1507-1679) made in E.coli
- Isotype: IgG1 kappa
- Recommended controls: 293 cell extract
Target Details
- Target: Human FANCM (Fanconi anemia, complementation group M)
- Tissue cell line specificity: 293 cell extract
- Target background: Fanconi anemia, complementation group M. Fanconi anemia-associated polypeptide of 250 kDa. ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
Applications
- Application: IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
