Anti-eAg Antibody from X63 Fused CD19 B Cell Hybridoma (F8)

Regulatory B cells (Bregs) have been shown to play a role in inflammatory bowel disease (IBD) in humans, as B cell depletion in patients with IBD tends to aggravate the disease. Furthermore it has been demonstrated that co-transfer of eAg-exposed B cells improves symptoms of experimental colitis in the T cell transfer model of colitis. […]

Contributors

Inventor Institute
Anders Elm Pedersen ; Mogens H Claesson University of Copenhagen
Cat. #: 153819
Unit size: 100 ug
Research Fields: Other
Target: Enteroantigen
Clone: F8
Class: Monoclonal
Product description: Regulatory B cells (Bregs) have been shown to play a role in inflammatory bowel disease (IBD) in humans, as B cell depletion in patients with IBD tends to aggravate the disease. Furthermore it has been demonstrated that co-transfer of eAg-exposed B cells improves symptoms of experimental colitis in the T cell transfer model of colitis. This eAg-specific B cell hybridoma offers a unique tool to investigate the immune response towards eAg’s in experimental colitis, and potentially,…
Conjugation: Unconjugated
Target background: Regulatory B cells (Bregs) have been shown to play a role in inflammatory bowel disease (IBD) in humans, as B cell depletion in patients with IBD tends to aggravate the disease. Furthermore it has been demonstrated that co-transfer of eAg-exposed B cells improves symptoms of experimental colitis in the T cell transfer model of colitis. This eAg-specific B cell hybridoma offers a unique tool to investigate the immune response towards eAg’s in experimental colitis, and potentially,…
Format: Liquid
Concentration: 0.9-1.1mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

In vitro cloning and regulatory potential of B cell hybridomas secreting entero-antigen specific antibody.

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