Decay Accelerating Factor is a distinctive marker of synovium. Decay Accelerating Factor protects tissues from attack by autologous complement by interfering with the assembly of C3 convertase.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151060 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | FACS ; IHC ; IF ; WB |
| Target: | Decay accelerating factor (DAF, CD55) |
| Reactivity: | Human |
| Clone: | 67 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD55 |
|---|---|
| Product description: | Decay Accelerating Factor is a distinctive marker of synovium. Decay Accelerating Factor protects tissues from attack by autologous complement by interfering with the assembly of C3 convertase. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 79 kDa |
| Immunogen: | Fibronectin purified human monocytes . |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Decay Accelerating Factor is a distinctive marker of synovium. Decay Accelerating Factor protects tissues from attack by autologous complement by interfering with the assembly of C3 convertase. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Gheorghe et al. 2011. PLoS One. 6(1):e16378. PMID: 21298002. Prostaglandin E2 synthesizing enzymes in rheumatoid arthritis B cells and the effects of B cell depleting therapy on enzyme expression. Kamada et al. 2009. Pathol Int. 59(6):382-9. PMID: 19490468. Leitinger et al. 2002. J Cell Sci. 115(Pt 5):963-72. PMID: 11870215. The involvement of lipid rafts in the regulation of integrin function. Palmer et al. 1985. Clin Exp Immunol. 59(3):529-38. PMID: 3886218. Features of synovial membrane identified with monoclonal antibodies. |
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