Cat. #154746
Anti-Cytokeratin 18 [DEK18]
Cat. #: 154746
Sub-type: Primary antibody
Unit size: 100 ug
Target: Cytokeratin 18
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP ; WB
Reactivity: Dog ; Human ; Feline
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Arnoud Sonnenberg
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytokeratin 18 [DEK18]
- Alternate name: KRT18; Keratin 18
- Research fields: Cancer;Cell biology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 48 kDa
- Strain: Balb/c
- Reactivity: Dog ; Human ; Feline
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP ; WB
- Description: Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene
- Immunogen: Cytoskeletal preperation extracted from humen epidermis
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Cytokeratin 18
- Molecular weight: 48 kDa
- Target background: Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene
Applications
- Application: FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Glebov et al. 2006. Nat Cell Biol. 8(1):46-54. PMID: 16341206.
- Bonfrer et al. 1994. Tumour Biol. 15(4):210-22. PMID: 7524130.
- Vos et al. 1992. Zentralbl Veterinarmed A. 39(10):721-40. PMID: 1283472.
