#152599

Anti-Cytochrome P450 27A1 [V29-P4B8*B2]

Cat. #152599

Anti-Cytochrome P450 27A1 [V29-P4B8*B2]

Cat. #: 152599

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1), Sterol 27-Hydroxylase

Class: Monoclonal

Application: IHC ; WB ; ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Cytochrome P450 27A1 [V29-P4B8*B2]
  • Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
  • Clone: V29-P4B8*B2
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; WB ; ELISA ; IHC ; WB
  • Description: Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
  • Immunogen: Ovalbumin-conjugated synthetic peptide KVVLAPETGEL (C-terminal sequence)
  • Isotype: IgG1 kappa
  • Recommended controls: IHC: formalin-fixed, paraffin-embedded human sections; WB: Overexpression lysates

Target Details

  • Target: Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1), Sterol 27-Hydroxylase
  • Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded human sections; WB: Overexpression lysates
  • Target background: Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.

Applications

  • Application: IHC ; WB ; ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -20° C
  • Shipping conditions: Shipping at 4° C

References

  • Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
  • Swan et al. 2016. Oncotarget. :. PMID: 27341022.